Anemia (Hb < 10 g/dL) was associated with significantly lower survival (RR 2.278, CI 95% 2.120–2.448, Table 3; survival 43.79% vs. 74.11% at five years, p < 0.001, Figure 1B) as well as a significantly higher risk of AML transformation (RR 6.096, CI 95% 4.124–9.010, Table 3), cachexia (RR 3.052, CI 95% 2.264–4.114, Table 3), SIRS (RR 2.970, CI 95% 2.485–3.550, Table 3), hemorrhage (RR 1.406, CI 95% 1.206–1.641, Table 3) and thrombosis (RR 1.919, CI 95% 1.587–2.320, Table 3). Here, GSTM1 is linked to Cachexia.