B4GALT3 and hepatocellular carcinoma: Human HCC cells (CSQT-2 and HCC-LM3) secrete exosomal miR-1247-3p, which decreases β-1,4-galactosyltransferase III (B4GALT3) expression, activating the β1-integrin/NF-κB pathway in fibroblasts that become CAFs [83].