For instance, the inclusion criteria for the KEYNOTE 010, KEYNOTE 024, and CHECKMATE 026 trials involved PD-L1 tumor-expression positivity, while by contrast, the CHECKMATE 017 and CHECKMATE 057 trials enrolled patients with NSCLC without considering their PD-L1 status [64]. The gene discussed is CD274; the disease is non-small cell lung carcinoma.