Overexpression of vimentin contributes to several cancers’ progression, invasion, and/or metastasis, including breast [73,74], ovarian [75], prostate [76,77], lung [78], colorectal cancers [79], tumors of the central nervous system [80] and gastrointestinal tract [81], malignant melanoma [82,83], and also head and neck squamous cell carcinoma [44,63]. The gene discussed is VIM; the disease is head and neck squamous cell carcinoma.