However, the other study, which involved samples from 1339 patients with invasive breast cancer, concluded NDRG3′s potential tumor promoter role in breast cancer: patients with NDRG3+ tumors had worse overall survival than patients with NDRG3– tumors, and NDRG3 independently predicted worse overall and disease-free survival [78]. This evidence concerns the gene NDRG3 and neoplasm.