The cancer-specific MUC1 glycoforms, carrying the sialylated core 1 glycan (α2,3-MUC1-sT), could induce macrophages to display a tumor-associated phenotype (TAM), also defined as alternatively activated (M2) pro-tumorigenic macrophages, through the engagement of Siglec-9 [54]. This evidence concerns the gene MUC1 and neoplasm.