Similarly, CD3+/CD8+/CD57+ and CD3+/CD4+/CD8dim/CD57+ phenotypes have been reported in T-LGL with STAT3 mutation, while CD3+/CD4+/CD57+ and CD3+/CD56+ are found in STAT5b mutation [75]. The gene discussed is CD8A; the disease is T-cell large granular lymphocyte leukemia.