Palpan Flores et al. investigated the equivalent of WV in 44 IDH-wildtype GBM patients and found a significant effect of WV > 60 cm3 in univariable and multivariable models (adjusted HR 3.93 95% CI 1.23–10.2, p = 0.018) [38]. This evidence concerns the gene IDH1 and glioblastoma.