Diagnostic criteria for cachexia include, in the case of cancer, a weight loss of at least 5% over 3–6 months or a BMI < 20 kg/m2 as the primary criterion [17], and, additionally, decreased muscle strength, fatigue, anemia, low free fat mass index (FFMI), decreased albumin levels, and increased proinflammatory cytokines, e.g., C-reactive protein. The gene discussed is CRP; the disease is Cachexia.