EGFR and head and neck squamous cell carcinoma: Epidermal growth factor receptor (EGFR) is a prime target in therapeutic development since numerous malignancies, including colorectal carcinoma (CRC) [15,16], non-small cell lung cancer (NSCLC) [17,18], and head and neck squamous cell carcinoma (HNSCC) [19,20], have abnormal overexpression of EGFR.