CXCL8 and chronic obstructive pulmonary disease: Accordingly, lower values of IL-8 were found at baseline in patients affected by NSCLC and COPD, predicting longer overall survival (OS) and progression-free survival (PFS) in some studies [7,93], probably acting through a reduction in oxidative stress [94], epithelial–mesenchymal transition [95], angiogenesis [96], immunosuppression, and gathering MDSCs [96].