Finally, an adipokine of great importance in energy metabolism is adiponectin, which avoids endothelial apoptosis and has the ability to neutralize oxidative stress and its deleterious effects because adiponectin decreases the production of ROS in endothelial cells to enhance vascular function [38]; therefore, we hypothesize that the increase recorded in placenta could be a compensatory mechanism to cope with the increased oxidative stress in mothers suffering from COVID-19 [26]. This evidence concerns the gene ADIPOQ and COVID-19.