GPT and acute kidney injury: After IPW, in patients with abnormal AST/ALT ratios, the causal relative risk of 60-day mortality, shock, acute kidney failure, treatment with inotropes and/or vasopressors, mechanical ventilation, and support-veno-arterial extracorporeal membrane oxygenation was significantly increased at 9.2 (95% confidence interval: 3.3–25.3), 10.1 (4.3–24), 1.9 (1.1–3.4), 2.7 (1.4–5.2), 2.3 (1.4–5.2), 5.7 (1.4–23.1), respectively (Figure 3).