ACE and obesity due to melanocortin 4 receptor deficiency: On the other hand, obesity (OR 0.79 [0.50–1.25, 95% CI], p = 0.31), hypertension (OR 1.19 [0.98–1.50, 95% CI], p = 0.08), male sex (OR 0.73 [0.48–1.1, 95% CI], p = 0.729), cigarette smoking (OR 1.5 [0.90–2.7, 95% CI], p = 0.114), number of comorbidities (OR 1.1 [0.97–1.23, 95% CI], p = 0.144), number of medications (OR 1.02 [0.91–1.14], 95% CI, p = 0.716), being on therapy with ACE inhibitors or Angiotensin Receptor blockers (ACE-I/ARBS, OR 0.78 [0.53–1.14], 95% CI, p = 0.196) did not show a significant correlation with mortality (Figure 1).