Emery–Dreifuss muscular dystrophy (EDMD) is a neuromuscular disorder caused by mutations in genes encoding nuclear envelope proteins, such as lamin-A (LMNA) (OMIM: 310300) and emerin (EMD) genes (OMIM: 181350). The gene discussed is LMNA; the disease is Emery-Dreifuss muscular dystrophy.