INS and type 1 diabetes mellitus: A combination of strategies may help prevent DKA in patients with T1D treated with SGLT2-is as follows: education to balance carbohydrate and insulin intake; specialized training to monitor ketone levels regularly, and especially in the presence of symptoms that may indicate the presence of ketosis; and the ability to apply the “STOP DKA PROTOCOL” and adjust therapy as appropriate, which is also very important.