BMPR2 and pulmonary arterial hypertension: Mutation of the TGF‐β family member BMPRII has been observed in familial PAH (~27% of cases) (Aldred et al., 2006; Cogan et al., 2006; Newman et al., 2004), and dysregulation of BMPR2 signaling has also been implicated in the pathogenesis of idiopathic PAH (Andruska & Spiekerkoetter, 2018).