The activation state of CD11b+ cells was compared with the neurodegenerative microglia (MGnD, ) which was established from different mouse models of neurological diseases including ALS, AD and multiple sclerosis (MS) [34]; with disease-associated microglia (DAM) described in an AD and ALS transgenic mouse models [35]; and with a specific subset of phagocytic microglia described in the same AD model [36](Table 1). Here, ITGAM is linked to amyotrophic lateral sclerosis.