KEGG pathway analysis showed that VMDEGs were significantly enriched in 30 KEGG pathways, some of which were related to tumor vasculogenic mimicry and metastasis, including PI3K − Akt signaling pathway; HIF-1 signaling pathway; Focal adhesion; MAPK signaling pathway; VEGF signaling pathway (Fig. S3A-B). The gene discussed is AKT1; the disease is neoplasm.