BCL2 and diffuse large B-cell lymphoma: Staudt and colleagues [14, 15] developed the LymphGen algorithm, and identified six genetic subtypes of DLBCL, including MCD (MYD88 L265P and CD79B co-mutated), BN2 (BCL6 fusions and NOTCH2 mutations), N1 (NOTCH1 mutations), EZB (EZH2 mutations and BCL2 translocations), ST2 (SGK1 and TET2 mutations), and A53 (TP53 mutations and deletions).