ATG7 and chronic obstructive pulmonary disease: Although studies have indicated that EVs derived from smoking-induced bronchial epithelial cells can promote differentiation and inhibit autophagy in lung fibroblasts by upregulating miR-210 and targeting ATG7 [42], the impact of relevant miRNAs in EVs secreted by bronchial epithelial cells on the pathophysiology of COPD remains poorly understood.