CD8A and neoplasm: In an actual publication, it has been shown in glioblastoma, that CXCL11 had a potent antitumor effect and reprogrammed the immunosuppressive tumor microenvironment, in which increased infiltration of CD8 T cells, NK cells and M1 macrophages, but decreased abundances of myeloid-derived suppressor cells (MDSCs), regulatory T cells (Tregs) and M2-polarized macrophages were observed [57].