IFNG and infection: Moreover, an elevated level of IFN-γ was observed in male patients with severe infection (466.9 ± 40.28) compared to male patients with non-severe infection (343.8 ± 28.31) (P = 0.02), as well as in female patients with severe infection (585.7 ± 49.50) compared to female patients with non-severe infection (287.8 ± 26.70) (P = 0.001) (Fig. 2.D).