In the scenario of tumor-specific TEX cells, congenic naive P14 CD8+ T cells were adoptively transferred into C57BL/6 recipients, which were then subcutaneously engrafted with syngeneic B16F10 melanoma cells expressing the LCMV GP (hereafter referred to as B16-GP cells)19 and killed on day 15 after tumor engraftment to analyze tumor-specific P14 TEX cells (Extended Data Fig. 1b). The gene discussed is CD8A; the disease is neoplasm.