Subgroup K-M survival curves based on CCDC58 expression levels were plotted to evaluate the role of CCDC58 in predicting survival value in LIHC patients with different variable groups, including age (Fig. S3A), gender (Fig. S3B), body mass index (BMI, Fig. S3C), albumin (Fig. S3D), AFP (Fig. S3E), prothrombin time (Fig. S3F), tumor status (Fig. S3G), pathologic T stage (Fig. S3H), pathologic stage (Fig. S3I). This evidence concerns the gene AFP and neoplasm.