Although further research is necessary to clarify the role of ZIP13 in the physiological functions of affected tissues including the heart and skeletal muscles, the patient-derived iPSCs established in the present study could be useful not only to uncover the mechanisms underlying ZIP13-mediated biological functions, but can also facilitate regenerative studies and pharmaceutical applications for the treatment of EDSSPD3. The gene discussed is SLC39A13; the disease is Ehlers-Danlos syndrome, spondylocheirodysplastic type.