Firstly, to determine if the long non-coding RNAs MEG3, MEG8, and MEG9 could predict expression of miRNAs from the Dlk1-Dio3 locus, we used paired bulk RNA and miRNA expression data for glioblastoma tumors from the CPTAC dataset to determine the correlation of an aggregated expression of Dlk1-Dio3 miRNAs with each gene in the RNA dataset. This evidence concerns the gene DIO3 and glioblastoma.