NR4A1 and neoplasm: Moreover, investigations suggest that breastfeeding duration plays a crucial role, revealing a dose–response relationship wherein longer periods of breastfeeding confer a more substantial risk reduction.[6] Furthermore, beyond lowering overall breast cancer risk, breastfeeding appears to exert nuanced effects on tumor biology, showing associations with reduced risks of certain aggressive breast cancer subtypes, such as hormone receptor-negative and triple-negative breast cancers.