SLC12A3 and Gerstmann syndrome: Gitelman syndrome (GS) (OMIM: 263800) is an autosomal recessive disorder caused by structural and/or functional abnormalities in the thiazide diuretic sensitive sodium chloride co-transporter encoded by the SLC12A3 gene mutation, characterized by hypokalemic alkalosis, hypomagnesemia, and low urinary calcium.[1,2] There is significant heterogeneity in the clinical characteristics of GS patients.[3] There have been no reports of GS combined with Graves disease and adrenocortical adenoma both domestically and internationally.