SMO and ameloblastoma: Additional studies showed gene expression profile differences between plexiform and follicular ameloblastomas, with follicular ameloblastomas expressing variants of BRAF, KMT2D, and ABL1, while plexiform ameloblastomas expressed variants of ALK, BRAF, KRAS, KMT2D, SMO, KMT2A, and BRCA2 [33, 34].