Another relevant intervention to study in these models could be CXCL1‐receptor antagonists, with CXCL1 being the functional homologue of human IL‐8 (a potent neutrophil attractant and activator), which might precede development of ARDS and seems to be of particular importance in COVID‐19 ARDS. This evidence concerns the gene CXCL1 and acute respiratory distress syndrome.