Expression levels of other activin A target genes, including Adam12, Pmepa1, and Lmcd1—known to be involved in receptor endocytosis, fibrogenesis, and tumor progression [40,41,42,43]—were significantly elevated by activin A (confirming our previous studies) [9], and entirely antagonized by NUCC-555. The gene discussed is PMEPA1; the disease is neoplasm.