PPIF and amyotrophic lateral sclerosis: Such ALS-related pathological processes as excitotoxicity [86] with a reduced calcium buffering capacity of the cytosol and mitochondria [87], overproduction of ROS and ONOO- [88], nitration of proteins including CypD and ANT [89], ATP level decrease, disturbances in mitochondrial dynamics [90], mitochondrial swelling and vacuolization [91], appear as triggers and consequences of mPTP opening [92].