In glioblastomas, however, a non-significant trend was observed for PFS (HR = 1.33 (0.94–1.9), p = 0.11) and OS (HR = 1.37 (0.94–1.98), p = 0.1) where the REN altered group (n = 36) had shorter PFS (6.7 months) and OS (11.1 months) compared to the non-altered group (n = 542) (PFS: 7.2 months, OS: 14.5 months) (Figure S3). This evidence concerns the gene REN and glioblastoma.