Notably, these DEGs displayed enrichment in critical signaling pathways, such as the TNF signaling pathway, the NF-kappa B signaling pathway, the C-type lectin receptor signaling pathway, the cytokine–cytokine receptor signaling pathway, the G protein-coupled receptor signaling pathway, the chemokine-mediated signaling pathway, the FoxO signaling pathway, nuclear receptor activities, sequence-specific DNA binding, and pathways in cancer. Here, TNF is linked to cancer.