Most pancreatic cancers are sporadic, but there is a small group of patients related to hereditary cancer-predisposing syndromes such as BRCA1/2 mutation, familial pancreatic cancer, Peutz-Jeghers, Lynch, Li-Fraumeni syndromes and familial atypical multiple mole melanoma [69]. Here, BRCA1 is linked to familial pancreatic carcinoma.