These include a human IgG-based tetravalent anti-CD99 antibody [41], or a branched multi-peptide composed of ERBB2, BIRC5, and CD99 to generate alpha-type 1 polarized dendritic cells, thereby stimulating cytotoxic T-lymphocyte to exert cytotoxic activity against glioblastoma cell lines and primary cultures [42]. The gene discussed is ERBB2; the disease is glioblastoma.