NEFL and dementia: When considering the A‐T‐N neuropathological cascade of developing dementia,2 these results may imply that such low plasma Aβ42/40 levels or high p‐τ181 and NfL levels cause neurodegeneration or neuroaxonal brain injury and were sufficiently increased to exert a maximum influence on dementia risk, especially in the case of NfL.4