A novel lncRNA termed lncMER52A with exclusive expression in HCC has been identified, and lncMER52A could promote HCC progression via stabilizing p120-catenin and activating p120-ctn/Rac1/Cdc42 axis both in vitro and in vivo (Wu et al., 2020) (Figure 5). This evidence concerns the gene CDC42 and hepatocellular carcinoma.