CYP19A1 and polycystic ovary syndrome: Furthermore, PCOS women exhibit significantly higher total serum BPA exposure compared to the control group (PCOS: 167.04 ± 9.44 IU/mL, control: 31.94 ± 3.57 IU/mL), suggesting that higher BPA level in the follicular fluid of PCOS patients (PCOS: 440.50 ± 63.70 pg/mL, control: 338.00 ± 57.88 pg/mL) may play a crucial role in its pathogenesis by reducing aromatase expression in granulosa cells (Wang et al., 2017; Prabhu et al., 2023).