SOD1 and Insulin resistance: A patent disclosed that the flavonoids could remarkably reduce blood glucose; improve the disturbance of lipid metabolism; increase the C-peptide level and the content of insulin in the serum; improve the excretion index of β cells of insulin and insulin resistance; reduce the insulin resistance index, malondialdehyde content in the blood serum, and contents of IL-1β, IL-6, and TNF-α; and improve superoxidase dismutase (SOD) activity (Jin et al., 2008).