TLR1 and hepatocellular carcinoma: In line with that, application of a DNAJB1-PRKACA fusion transcript-based peptide-vaccine adjuvanted with the TLR1/2 agonist XS15 emulsified in Montanide ISA 51 VG in one FL-HCC patient was well tolerated and showed the induction of profound and long-lasting T-cell responses accompanied by long-term disease-free survival (36).