Each SD increase in TGF-alpha (OR = 1.16, 95% CI = 1.15-1.17, P-value = 3.33e-248) and CX3CL1 (OR = 1.30, 95% CI = 1.04-1.63, P-value = 0.0199) was associated with an increased risk of developing type 2 diabetes. Here, TGFA is linked to type 2 diabetes mellitus.