↑ Akkermansia genusIn RA patients with high levels of TNF-α or IL-17A compared with control:↑ Gammaproteobacteria phylum↑ Enterobacteriaceae and Klebsiella↓ BifidobacteriumIn RA-active patients vs RA-inactive patients:↑ Collinsela and Akkermansia generaPositive correlations:Euryarchaeota phylum and IL-6Euryarchaeota phylum and IL-17. The gene discussed is TNF; the disease is rheumatoid arthritis.