Multifactorial COX regression analysis showed (Table 3) that baseline IL-8 (HR=3.852, 95% CI 1.561-9.508, p=0.003) and the percentage of the CD16brightCD62Ldim neutrophil subtype (HR=5.305, 95% CI 1.986-14.165, p=0.001) were independent risk factors for the development of infectious complications in patients with sepsis-related ARDS. This evidence concerns the gene CXCL8 and acute respiratory distress syndrome.