In patients with lung cancer who also experienced OSA, IH induced a decrease in the expression of microRNA-320b, with downstream expression of ubiquitin-specific peptidase 37 (USP37) upregulated secondary to IH and USP37 promoting lung cancer progression by mediating the deubiquitination of Cdc10-dependent transcript 1 (CDT1) (98). This evidence concerns the gene USP37 and obstructive sleep apnea syndrome.