Notably, this was missing in RP13-ROs, which also showed decreased immunostaining for cone (OPN1LW/MW), rod (rhodopsin) and retinal ganglion cell (SNCG) markers (Fig. 1E, F), suggesting an overall reduction in red/green cone and rod photoreceptor numbers, recapitulating the RP disease phenotype. Here, RHO is linked to retinitis pigmentosa 1.