Previous studies have shown that patients with severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) have widespread systematically related persistent symptoms [5], while SARS-CoV-2 is associated with severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) belongs to the same family of coronaviruses, the genus Coronavirus β, has a similar viral structure [6], especially with SARS-CoV has a specific binding receptor Angiotensin-converting enzyme 2 (ACE2) [7], thus play a pathogenic role. The gene discussed is ACE2; the disease is Middle East respiratory syndrome.