The present study showed significant differences in CD86 expression, neutrophil count, CRP/ALB, NLR, IL-6, IL-10, sIL-2R, CRP, PCT, HLA-DR, lymphocytes, PLT, ALB, and LMR between patients with sepsis and those with non-septic infections, consistent with the presence of immune disorders in patients with sepsis [10]. The gene discussed is CD86; the disease is immune system disorder.