TIMP2 and acute kidney injury: Several biomarkers have been reported to be associated with AKI in sepsis, including procalcitonin [19], microRNA-22-3p [20], neutrophil gelatinase-related lipoproteins [21], urine miR-26b [22], soluble thrombomodulin [23], Tissue Inhibitor of Metalloproteinase-2(TIMP-2), and Insulin-like Growth factor-Binding Protein 7 (IGBP-7) [24].